Primary Progressive Aphasia Associated With GRN Mutations: New Insights into the Non-amyloid Logopenic Variant

Dario Saracino, Sophie Ferrieux, Marie Noguès-Lassiaille, Marion Houot, Aurélie Funkiewiez, Leila Sellami, Vincent Deramecourt, Florence Pasquier, Philippe Couratier, Jérémie Pariente, Amandine Géraudie, Stéphane Epelbaum, David Wallon, Didier Hannequin, Olivier Martinaud, Fabienne Clot, Agnès Camuzat, Simona Bottani, Daisy Rinaldi, Sophie Auriacombe, Marie Sarazin, Mira Didic, Boutoleau-Bretonnière Claire, Christel Thauvin-Robinet, Julien Lagarde, Carole Roué-Jagot, François Sellal, Audrey Gabelle, Frédérique Etcharry-Bouyx, Alexandre Morin, Cinzia Coppola, Richard Levy, Bruno Dubois, Alexis Brice, Olivier Colliot, Maria Luisa Gorno-Tempini, Marc Teichmann, Raffaella Migliaccio, Isabelle Le Ber, French research network on FTD/FTD-ALS

Neurology DOI: 10.1212/WNL.0000000000012174

Selezionato dal Lettore: dott.ssa Domiziana Rinaldi - Università "La Sapienza" di Roma

MOTIVATION: This cross-sectional study, showing that the most frequent PPA variant associated with GNR mutations is non-amyloid logopenic PPA, is important in clinical practice for the development of GNR gene-specific therapies.